CBD does not bind to the endocannabinoid receptors. CBG can bind to both of the receptors in the endocannabinoid system, CB1, and CB2. CB1 is located in the brain and nervous system, and CB2 is located in the gut or immune system.
Because of its ability to bind to both receptors, CBG can impact the physical body in a few important ways. While research is preliminary, it is very promising. Studies are finding that CBG can support immune health, act as a neuroprotectant, support gastrointestinal health (specifically for inflammatory diseases of the gut), and help modulate symptoms of glaucoma.
CBG strengthens anandamide, an endocannabinoid that boosts dopamine levels and regulates appetite and sleep. It also impacts how we experience pleasure and motivation. Users of CBG also notice support with pain and inflammation. Many folks also enjoy an energy boost and a feeling of greater clarity of mind after taking CBG isolate.
CBG can be combined with other cannabinoid extracts or products to boost cannabinoid synergy, which is also known as the “entourage effect.” The entourage effect describes what happens when cannabinoids are ingested together, creating a more synergistic impact than if they were consumed alone.